Details

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Manufacturer

Duopharma Manufacturing

Registration number

MAL20032257AZ

Content

Ofloxacin 400 mg
 

Indications

Used for treatment of infections caused by susceptible bacteria, such as:

• Respiratory tract: e.g., bronchitis, pneumonia.

• Urinary tract and prostate: e.g., cystitis, pyelonephritis, prostatitis.

• Skin & soft tissue, sexually transmitted infections (e.g., gonorrhoea, chlamydia).

Instructions 

1. Dosage:

   • Typically 400 mg once or twice daily, depending on infection (e.g. 400 mg q12h for respiratory/skin; single 400 mg dose for uncomplicated gonorrhoea) 

   • In urinary infections, may start 200 mg daily and escalate to 400 mg twice daily if required .

2. Administration:

   • Take with or without food; swallow with plenty of water.

   • Avoid antacids, iron, zinc 2 hours before/after dose (can reduce absorption) 

3. • Generally 3–14 days depending on indication; single dose for uncomplicated gonorrhoea.

   • Complete full prescribed course, even if symptoms improve 

4. Dose adjustments:

   • In renal impairment (CrCl <50 mL/min): dosing frequency reduced (e.g., q24h or half dose) .

   • No dose change required purely for age, but monitor renal function in elderly 
     
     Cautions:

     • Avoid in pregnancy, lactation, children/adolescents due to musculoskeletal risks 

     • Watch for serious side effects: tendonitis/rupture, neuropathy, CNS effects—stop and seek medical help if experienced 

     • Avoid excessive sunlight exposure due to photosensitivity risk.