Details

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Manufacturer

Sunward Pharmaceutical Sdn. Bhd.

Registraction Number

MAL20051301ASZ

Content

Metoclopramide Hydrochloride

 

Indications

• Sunward Metoclopramide 10 mg Tablet is indicated for:

  • Symptomatic treatment of nausea and vomiting, including that associated with acute migraine-induced nausea and vomiting in adults.

  • Prevention of delayed chemotherapy-induced nausea and vomiting (CINV) and radiotherapy-induced nausea and vomiting (RINV) in adults.

  • Second-line option in the prevention of delayed CINV in children aged 1–18 years

 

Instructions

• Dosage:

  • Adults: Recommended single dose is 10 mg, repeated up to three times daily. Maximum daily dose is 30 mg. Duration: up to 5 days.

  • Children (1–18 years): Dosage is based on body weight (0.1–0.15 mg/kg per dose, up to three times daily). Maximum daily dose is 0.5 mg/kg. 

• Administration: Should be taken on an empty stomach; take 30 minutes before meals. 

• Precautions:

  • Contraindicated in patients with hypersensitivity, gastrointestinal (GI) hemorrhage, mechanical obstruction, GI perforation, pheochromocytoma, history of neuroleptic- or metoclopramide-induced tardive dyskinesia, epilepsy, Parkinson's disease, or known history of methemoglobinemia. 

  • Use with caution in patients with underlying neurological disorders, cardiac conduction disorders, electrolyte imbalance, bradycardia, high dose & long-term treatment, concomitant use with other centrally-acting drugs, drugs prolonging QT interval, end-stage renal disease (CrCl ≤15 mL/min), moderate to severe renal impairment (CrCl 15–60 mL/min), severe hepatic impairment, pregnancy & lactation, and elderly.

  • Not suitable for children weighing less than 30 kg