Details
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Marketing Authorisation (MAL): MAL15125063ARZ.
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Manufacturer: Novartis Farma S.p.A., Italy.
Content
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Active Ingredients per Tablet:
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Sacubitril: 97.2 mg
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Valsartan: 102.8 mg
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Formulation: Light pink ovaloid biconvex film-coated tablet with bevelled edges, unscored, debossed with "NVR" on one side and "L11" on the other side.
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Pack Size: 60 tablets per pack.
Indications
Entresto is indicated for the treatment of chronic heart failure with reduced ejection fraction (HFrEF) in adults to reduce the risk of cardiovascular death and hospitalization due to heart failure. It is administered in place of an ACE inhibitor or angiotensin II receptor blocker (ARB). Benefits are most evident in patients with left ventricular ejection fraction below normal.
Instructions
Dosage:
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Starting Dose: One tablet of 100 mg twice daily.
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Titration: Increase to one tablet of 200 mg twice daily after 2–4 weeks, as tolerated by the patient.
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Hypertension: For essential hypertension, the recommended starting dose is 200 mg once daily, which may be increased to 400 mg once daily if blood pressure is not adequately controlled.
Administration:
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Take the tablet orally with or without food.
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Swallow the tablet whole; do not split or crush.
Missed Dose:
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If a dose is missed, take it as soon as you remember.
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If it's almost time for your next dose, skip the missed dose.
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Do not take two doses at the same time to make up for a missed dose.
Storage:
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Store at room temperature, away from moisture and heat.
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Keep out of reach of children.
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