Details

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Manufacturer
S.A. Alcon-Couvreur N.V., Belgium

Registraction Number
MAL20081847AZ
 

• Active Ingredient: Each 1 mL contains 20 mg of pilocarpine hydrochloride, equivalent to a 2% concentration.

• Preservative: Contains benzalkonium chloride (0.01%) as a preservative.

• Manufacturer & MAL Number: Manufactured by S.A. Alcon-Couvreur N.V., Belgium; marketed in Malaysia by Novartis Corporation (Malaysia) Sdn. Bhd. with MAL number: MAL20081847AZ.
  
   

  Active Ingredient and Composition

• Active Ingredient: Pilocarpine hydrochloride 20 mg/mL (2%)

• Preservative: Benzalkonium chloride

• Other Ingredients: Boric acid, citric acid, hydrochloric acid, hydroxypropyl methylcellulose, purified water, sodium chloride, sodium citrate, sodium hydroxide
  
   

  Indications

  Isopto® Carpine 2% is indicated for:

• Reducing elevated IOP in patients with open-angle glaucoma or ocular hypertension

• Inducing miosis (pupil constriction) during certain eye surgeries

• Preventing postoperative elevated IOP following laser eye procedures

Dosage and Administration

• Adults: Instill one drop into the affected eye(s) up to four times daily. For pilocarpine-naïve patients, starting with the 1% concentration is recommended, as higher concentrations may not be well-tolerated initially.

• Acute Angle-Closure Glaucoma: One drop of Isopto® Carpine 1% or 2% may be applied topically in the eye(s) up to three times over a 30-minute period. If laser iridoplasty or iridotomy is used to break the attack, one drop of Isopto® Carpine 4% should be administered prior to the procedure. Following laser iridoplasty, one drop of Isopto® Carpine 1% should be administered four times daily until an iridotomy can be performed.

• Pediatric Use: In children under 2 years of age, one drop of Isopto® Carpine 1% should be applied topically in the eye(s) three times daily. Children 2 years of age and over should be dosed as for adults. For the induction of miosis prior to goniotomy or trabeculotomy in children, one drop of Isopto® Carpine 1% or 2% should be applied topically in the eye 15 to 60 minutes prior to surgery.