Imuran 50mg Tab

Imuran 50mg Tab

Category: Drug Info

Specifications
Details

Manufacturer
Aspen SA Operations (Pty) Ltd

Registraction Number

MAL19990042AZ



Content
  • Active Ingredient: Azathioprine 50 mg per tablet
  • Excipients: Each tablet contains pregelatinized maize starch
  • Formulation: Yellow, round, biconvex, film-coated tablets, scored, branded "IM 5"
  • Packaging: 100 tablets per bottle


Indication

Imuran 50mg Tablets are indicated for:
  • Organ Transplants: Prevention of rejection in kidney, liver, or heart transplants
  • Autoimmune Diseases: Treatment of conditions such as severe rheumatoid arthritis, systemic lupus erythematosus, chronic active hepatitis, pemphigus vulgaris, polyarteritis nodosa, autoimmune hemolytic anemia, and chronic refractory idiopathic thrombocytopenic purpura


Instructions
  • Dosage:
    • Organ Transplants:
      • Loading dose: 5 mg/kg body weight per day
      • Maintenance dose: 1–4 mg/kg body weight per day
    • Autoimmune Diseases:
      • Initial dose: 1–3 mg/kg body weight per day
  • Administration: Take tablets orally, preferably 1 hour before or 3 hours after meals to enhance absorption
  • Monitoring:
    • Regular blood tests to monitor blood cell counts and liver function
    • Adjustments may be necessary based on laboratory results
  • Contraindications:
    • Hypersensitivity to azathioprine or any component of the tablet
    • Pregnancy and breastfeeding
    • Active infections
  • Cautions:
    • Increased risk of infections and certain cancers due to immunosuppression
    • Use with caution in patients with liver or kidney impairment
    • Avoid live vaccines during treatment
  • Pregnancy Category: D (Risk to fetus exists; use only if potential benefit justifies the risk)
  • Breastfeeding: Not recommended due to potential excretion in breast milk


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