Details

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Manufacturer
DUOPHARMA (M) SDN. BHD.
 
Contents
Granisetron HCl
 
Indication
Treatment and prophylaxis of postoperative nausea and vomiting, Nausea and vomiting associated with cancer chemotherapy, Prophylaxis of nausea and vomiting associated with radiation therapy
 
Instruction
1-3 mg 5 min prior to start of radiotherapy, by infusion over 5 min or by bolus inj over at least 30 sec.
 
Drug interaction
Induced metabolism w/ phenobarbital. Risk of serotonin syndrome w/ other serotonergic agents e.g. SSRIs, and serotonin and norepinephrine reuptake inhibitors (SNRIs). Altered clearance w/ CYP enzyme inducers or inhibitors. Concomitant use w/ drugs known to prolong QT interval may result in clinical consequences.