Details

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Manufacturer
DUOPHARMA (M) SDN. BHD.
 
Contents
Dexamethasone
 
Indication
Anti-inflammatory or immunosuppressive, Screening test for Cushing's syndrome, Acute exacerbations in multiple sclerosis, Diagnostic test in differentiating pituitary and ectopic production of ACTH in patients with ACTH-dependent Cushing's syndrome.
 
Instruction
Should be taken with food.
 
Drug interaction
Decreased plasma concentration with CYP3A4 inducers (e.g. barbiturates, carbamazepine, ephedrine, phenytoin, rifabutin, rifampicin). Increased plasma concentration with CYP3A4 inhibitors (e.g. erythromycin, ketoconazole, ritonavir). May increase renal clearance of salicylates. May enhances hypokalaemic effects of diuretics (acetazolamide, loop, thiazide), amphotericin B injection, corticosteroids, carbenoxolone, and K-depleting agents. May enhance anticoagulant effect of warfarin.Potentially Fatal: May diminish therapeutic effect of live virus vaccines.