Details

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Manufacturer
DUOPHARMA (M) SDN. BHD.
 
Contents
Levodopa 100 mg, carbidopa 25 mg.
 
Indication
Monotherapy in Parkinson's disease.
 
Instruction
Should be taken on an empty stomach. May be taken w/ meals if GI discomfort occurs.
 
Drug interaction
Pyridoxine reverses effects of levodopa. Type-B MAOIs have synergistic effect. Effect reduced by phenothiazines, haloperidol, reserpine, pyridoxine, diazepam, oxazepam, chlordiazepoxide, phenobarbitone. Effects of levodopa enhanced by carbidopa, amantadine, anticholinergics, amphetamine. Effects of sympathomimetic agents enhanced.Potentially Fatal: Enhances hypotensive effects of bethanidine, bretylium, guanethidine. Hypertensive crises with furazolidone or MAO inhibitors.