Details

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Manufacturer
DUOPHARMA (M) SDN. BHD.
 
Contents
Neostigmine methylsulfate
 
Indication
Neonatal myasthenia gravis, Reversal of neuromuscular blockade, Paralytic ileus and postoperative urinary retention, Myasthenia gravis
 
Instruction
Administer via IM/IV.
 
Drug interaction
May potentiate neuromuscular blockade w/ depolarising muscle relaxants (e.g. suxamethonium) resulting to prolonged apnoea. Drugs w/ neuromuscular blocking activity (e.g. aminoglycosides, clindamycin, colistin, cyclopropane, halogenated inhalational anaesth) may antagonise the effects of neostigmine. Reduced effects w/ quinine, chloroquine, hydroxychloroquine, quinidine, procainamide, propafenone, lithium. Prolonged bradycardia w/ β-blockers.