Details

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Manufacturer
DUOPHARMA (M) SDN. BHD.
 
Contents
Imipramine
 
Indication
Depression and Nocturnal enuresis.
 
Instruction
May be taken with or without food.
 
Drug interaction
Increased plasma concentration w/ CYP2D6 isoenzyme inhibitors (e.g. cimetidine, quinidine). Increased plasma levels w/ hepatic enzyme inhibitors (e.g. cimetidine) and decreased plasma levels w/ hepatic enzyme inducers (e.g. barbiturates). May potentiate the effect of anticholinergic drugs, catecholamines and CNS depressants.Potentially Fatal: Hyperpyretic crises or severe convulsive seizures may occur when used concomitantly w/ MAOIs.