Details

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Manufacturer
PFIZER PHARMACEUTICALS LLC
 
Contents
Celecoxib
 
Indication
Management of acute pain in adults & treatment of primary dysmenorrhea. Relief of acute & chronic pain & inflammation of RA & OA. Relief of signs & symptoms of ankylosing spondylitis. Management of low back pain (200 mg only).
 
Instruction
May be taken with or without food.
 
Drug interaction
Increased plasma conc by CYP2C9 inhibitors. Decreased plasma conc w/ CYP2C9 inducers eg, rifampicin, carbamazepine & barbiturates. Increased lithium plasma levels. Diminished effect of antihypertensives eg, ACE inhibitors &/or ARBs, diuretics & β-blockers. Increased risk of nephrotoxicity w/ cyclosporine. Increased plasma conc of dextromethorphan & metoprolol. Reduced natriuretic effect of furosemide & thiazides.