Details

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Manufacturer
Pfizer Manufacturing Deutschland GmbH.
 
Contents
Axitinib
 
Indication
Axitinib is indicated for the treatment of adult patients with advanced renal cell carcinoma (RCC) after failure of prior treatment with sunitinib or a cytokine.
 
Instruction
May be taken with or without food.
 
Drug interaction
Increased plasma conc w/ CYP3A4/5 inhibitors (eg, ketoconazole, itraconazole, clarithromycin, erythromycin, atazanavir, indinavir, nefazodone, nelfinavir, ritonavir, saquinavir & telithromycin); grapefruit. Reduced plasma conc w/ CYP3A4/5 inducers (eg, rifampin, dexamethasone, phenytoin, carbamazepine, rifabutin, rifapentin, phenobarb & St. John's wort).