Details

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Manufacturer
FRESENIUS KABI AUSTRIA GMBH
 
Contents
Paracetamol
 
Indication
Fever, Mild to moderate pain
 
Instruction
Adult: 33-50 kg: 15 mg/kg 4-6 hourly if needed. Max: 3 g daily. >50 kg: 1 g 4-6 hourly if needed. Max: 4 g daily. Administer by infusion over 15 minutes.
Child: Full-term neonates and children <10 kg: 7.5 mg/kg as a single dose, at least 4 hourly. Max: 30 mg/kg/day; 10-33 kg: 15 mg/kg as a single dose, at least 4 hourly. Max: 2 g daily; 33-50 kg: 15 mg/kg as a single dose, at least 4 hourly. Max: 3 g daily; >50 kg: Same as adult dose.
 
Drug interaction
Decreased absorption with colestyramine. Decreased serum concentrations with rifampicin and some anticonvulsants (e.g. phenytoin, phenobarbital, carbamazepine, primidone). Enhances the anticoagulant effect of warfarin and other coumarins with prolonged use. Increased absorption with metoclopramide and domperidone. Increased serum concentration with probenecid. May increase serum concentration of chloramphenicol.