Details

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Manufacturer
XEPA-SOUL PATTINSON (MALAYSIA) SDN BHD
 
Contents
Dextromethorphan HBr
 
Indication
Cough suppressant.
 
Instruction
Adult: As dextromethorphan hydrobromide: As conventional preparation: 10-20 mg 4 hourly, or 30 mg 6-8 hourly. As extended-release preparation: 60 mg 12 hourly. Max: 120 mg daily. As loz: Suck not more than 12 loz daily.
Child: >12 years Same as adult dose.
 
Drug interaction
Additive CNS effect when used with antihistamines, psychotropics and other CNS depressants. Increased toxic effect when used with potent CYP2D6 enzyme inhibitors (e.g. fluoxetine, paroxetine, quinidine, terbinafine).
Potentially Fatal: Increased risk of serotonin syndrome (e.g. hyperpyrexia, hallucinations, gross excitation or coma) when concomitantly used with MAOIs or SSRIs.