Details

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Manufacturer

- DKSH Malaysia Sdn Bhd.

Registraction Number

- MAL19984319AZ

Contents

- Acyclovir
 

Indications

According to the product leaflet and clinical sources 

• Herpes zoster (shingles)

• Chickenpox (varicella)

• Herpes simplex virus (HSV) infections – initial and recurrent genital and mucocutaneous herpes

• Suppression of recurrent HSV, including prevention in immunocompromised patients
   

  Instructions

• Oral Use:

  • Swallow whole with water, with or without food; maintain consistent timing each day.

  • Hydrate well to support kidney function and reduce risk of nephrotoxicity 

• Typical Adult Dosage Regimens:

  • Shingles (herpes zoster): 800 mg every 4 hours, 5 times daily, for 7–10 days 

  • Chickenpox (varicella): 800 mg 4 times daily for ~5 days (adults and children >6 yr) 

  • Initial/recurrent HSV: 200 mg 5 times daily for 5–10 days; severe cases or immunocompromised may use 400 mg 5 times daily, or 800 mg in suppression regimens .

  • Suppressive therapy: often 800 mg daily in 2–4 divided doses (sometimes reduced to 400–600 mg) .

• Renal Impairment Adjustments:

  • Reduce dose/frequency based on creatinine clearance; elderly may require adjustment .

• Missed Dose:

  • Take ASAP unless near next dose; do not double dose .

• Avoid abrupt discontinuation in chronic suppressive regimens to reduce resistance or viral rebound.